HI Friends, log of virtual box as bellow, please help to check what is issue, thank you.
53e8.59d8: Log file opened: 5.2.16r123759 g_hStartupLog=0000000000000174 g_uNtVerCombined=0xa042ee00
53e8.59d8: \SystemRoot\System32\ntdll.dll:
53e8.59d8: CreationTime: 2019-09-16T02:12:12.563939900Z
53e8.59d8: LastWriteTime: 2019-05-17T06:06:58.140701600Z
53e8.59d8: ChangeTime: 2020-12-21T10:01:09.448823200Z
53e8.59d8: FileAttributes: 0x20
53e8.59d8: Size: 0x1da660
53e8.59d8: NT Headers: 0xe8
53e8.59d8: Timestamp: 0x7f828745
53e8.59d8: Machine: 0x8664 - amd64
53e8.59d8: Timestamp: 0x7f828745
53e8.59d8: Image Version: 10.0
53e8.59d8: SizeOfImage: 0x1e1000 (1970176)
53e8.59d8: Resource Dir: 0x174000 LB 0x6b3e8
53e8.59d8: [Version info resource found at 0xd8! (ID/Name: 0x1; SubID/SubName: 0x409)]
53e8.59d8: [Raw version resource data: 0x1740f0 LB 0x380, codepage 0x0 (reserved 0x0)]
53e8.59d8: ProductName: Microsoft® Windows® Operating System
53e8.59d8: ProductVersion: 10.0.17134.799
53e8.59d8: FileVersion: 10.0.17134.799 (WinBuild.160101.0800)
53e8.59d8: FileDescription: NT Layer DLL
53e8.59d8: \SystemRoot\System32\kernel32.dll:
53e8.59d8: CreationTime: 2019-09-16T02:12:06.560196800Z
53e8.59d8: LastWriteTime: 2019-04-19T10:54:56.743034000Z
53e8.59d8: ChangeTime: 2020-12-21T10:01:08.911869100Z
53e8.59d8: FileAttributes: 0x20
53e8.59d8: Size: 0xafd48
53e8.59d8: NT Headers: 0xe8
53e8.59d8: Timestamp: 0xda2d7146
53e8.59d8: Machine: 0x8664 - amd64
53e8.59d8: Timestamp: 0xda2d7146
53e8.59d8: Image Version: 10.0
53e8.59d8: SizeOfImage: 0xb1000 (724992)
53e8.59d8: Resource Dir: 0xaf000 LB 0x520
53e8.59d8: [Version info resource found at 0x90! (ID/Name: 0x1; SubID/SubName: 0x409)]
53e8.59d8: [Raw version resource data: 0xaf0b0 LB 0x3a4, codepage 0x0 (reserved 0x0)]
53e8.59d8: ProductName: Microsoft® Windows® Operating System
53e8.59d8: ProductVersion: 10.0.17134.753
53e8.59d8: FileVersion: 10.0.17134.753 (WinBuild.160101.0800)
53e8.59d8: FileDescription: Windows NT BASE API Client DLL
53e8.59d8: \SystemRoot\System32\KernelBase.dll:
53e8.59d8: CreationTime: 2020-12-14T02:00:12.242752400Z
53e8.59d8: LastWriteTime: 2019-11-28T05:10:04.805523000Z
53e8.59d8: ChangeTime: 2020-12-22T01:42:33.977945900Z
53e8.59d8: FileAttributes: 0x20
53e8.59d8: Size: 0x273c48
53e8.59d8: NT Headers: 0xf0
53e8.59d8: Timestamp: 0x8569b554
53e8.59d8: Machine: 0x8664 - amd64
53e8.59d8: Timestamp: 0x8569b554
53e8.59d8: Image Version: 10.0
53e8.59d8: SizeOfImage: 0x273000 (2568192)
53e8.59d8: Resource Dir: 0x251000 LB 0x548
53e8.59d8: [Version info resource found at 0x90! (ID/Name: 0x1; SubID/SubName: 0x409)]
53e8.59d8: [Raw version resource data: 0x2510b0 LB 0x3bc, codepage 0x0 (reserved 0x0)]
53e8.59d8: ProductName: Microsoft® Windows® Operating System
53e8.59d8: ProductVersion: 10.0.17134.1184
53e8.59d8: FileVersion: 10.0.17134.1184 (WinBuild.160101.0800)
53e8.59d8: FileDescription: Windows NT BASE API Client DLL
53e8.59d8: \SystemRoot\System32\apisetschema.dll:
53e8.59d8: CreationTime: 2018-04-11T23:34:44.042150700Z
53e8.59d8: LastWriteTime: 2018-04-11T23:34:44.042150700Z
53e8.59d8: ChangeTime: 2018-09-28T03:14:06.198870000Z
53e8.59d8: FileAttributes: 0x20
53e8.59d8: Size: 0x1bd98
53e8.59d8: NT Headers: 0xd0
53e8.59d8: Timestamp: 0xd02ff418
53e8.59d8: Machine: 0x8664 - amd64
53e8.59d8: Timestamp: 0xd02ff418
53e8.59d8: Image Version: 10.0
53e8.59d8: SizeOfImage: 0x1c000 (114688)
53e8.59d8: Resource Dir: 0x1b000 LB 0x408
53e8.59d8: [Version info resource found at 0x48! (ID/Name: 0x1; SubID/SubName: 0x409)]
53e8.59d8: [Raw version resource data: 0x1b060 LB 0x3a8, codepage 0x0 (reserved 0x0)]
53e8.59d8: ProductName: Microsoft® Windows® Operating System
53e8.59d8: ProductVersion: 10.0.17134.1
53e8.59d8: FileVersion: 10.0.17134.1 (WinBuild.160101.0800)
53e8.59d8: FileDescription: ApiSet Schema DLL
53e8.59d8: Found driver SRTSPX (0x2)
53e8.59d8: Found driver SymEvent (0x2)
53e8.59d8: Found driver SymIRON (0x2)
53e8.59d8: supR3HardenedWinFindAdversaries: 0x2
53e8.59d8: \SystemRoot\System32\drivers\symevent64x86.sys:
53e8.59d8: CreationTime: 2021-06-18T10:18:03.104788900Z
53e8.59d8: LastWriteTime: 2021-06-18T10:18:03.081363000Z
53e8.59d8: ChangeTime: 2021-06-18T10:18:03.081363000Z
53e8.59d8: FileAttributes: 0x20
53e8.59d8: Size: 0x18650
53e8.59d8: NT Headers: 0xe8
53e8.59d8: Timestamp: 0x5a95cc4b
53e8.59d8: Machine: 0x8664 - amd64
53e8.59d8: Timestamp: 0x5a95cc4b
53e8.59d8: Image Version: 6.3
53e8.59d8: SizeOfImage: 0x21000 (135168)
53e8.59d8: Resource Dir: 0x1f000 LB 0x3c8
53e8.59d8: [Version info resource found at 0x90! (ID/Name: 0x1; SubID/SubName: 0x409)]
53e8.59d8: [Raw version resource data: 0x1f0b8 LB 0x310, codepage 0x4e4 (reserved 0x0)]
53e8.59d8: ProductName: SYMEVENT
53e8.59d8: ProductVersion: 14.0.6.27
53e8.59d8: FileVersion: 14.0.6.27
53e8.59d8: FileDescription: Symantec Event Library
53e8.59d8: supR3HardenedWinInitAppBin(0x0): '\Device\HarddiskVolume3\Program Files\Oracle\VirtualBox'
53e8.59d8: Calling main()
53e8.59d8: SUPR3HardenedMain: pszProgName=VirtualBox fFlags=0x2
53e8.59d8: supR3HardenedWinInitAppBin(0x2): '\Device\HarddiskVolume3\Program Files\Oracle\VirtualBox'
53e8.59d8: SUPR3HardenedMain: Respawn #1
53e8.59d8: System32: \Device\HarddiskVolume3\Windows\System32
53e8.59d8: WinSxS: \Device\HarddiskVolume3\Windows\WinSxS
53e8.59d8: KnownDllPath: C:\windows\System32
53e8.59d8: '\Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe' has no imports
53e8.59d8: supHardenedWinVerifyImageByHandle: -> 0 (\Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe)
53e8.59d8: supR3HardNtEnableThreadCreation:
53e8.59d8: supR3HardNtDisableThreadCreation: pvLdrInitThunk=00007ffdf91f4f90 pvNtTerminateThread=00007ffdf921b3f0
53e8.59d8: supR3HardenedWinDoReSpawn(1): New child 398.3268 [kernel32].
53e8.59d8: supR3HardNtChildGatherData: PebBaseAddress=0000000000650000 cbPeb=0x388
53e8.59d8: supR3HardNtPuChFindNtdll: uNtDllParentAddr=00007ffdf9180000 uNtDllChildAddr=00007ffdf9180000
53e8.59d8: supR3HardenedWinSetupChildInit: uLdrInitThunk=00007ffdf91f4f90
53e8.59d8: supR3HardenedWinSetupChildInit: Start child.
53e8.59d8: supR3HardNtChildWaitFor: Found expected request 0 (PurifyChildAndCloseHandles) after 1 ms.
53e8.59d8: supR3HardNtChildPurify: Startup delay kludge #1/0: 514 ms, 40 sleeps
53e8.59d8: supHardNtVpScanVirtualMemory: enmKind=CHILD_PURIFICATION
53e8.59d8: *0000000000000000-00000000004effff 0x0001/0x0000 0x0000000
53e8.59d8: *00000000004f0000-000000000050ffff 0x0004/0x0004 0x0020000
53e8.59d8: *0000000000510000-0000000000528fff 0x0002/0x0002 0x0040000
53e8.59d8: 0000000000529000-000000000052ffff 0x0001/0x0000 0x0000000
53e8.59d8: *0000000000530000-0000000000533fff 0x0002/0x0002 0x0040000
53e8.59d8: 0000000000534000-000000000053ffff 0x0001/0x0000 0x0000000
53e8.59d8: *0000000000540000-0000000000540fff 0x0004/0x0004 0x0020000
53e8.59d8: 0000000000541000-00000000005fffff 0x0001/0x0000 0x0000000
53e8.59d8: *0000000000600000-000000000064ffff 0x0000/0x0004 0x0020000
53e8.59d8: 0000000000650000-0000000000652fff 0x0004/0x0004 0x0020000
53e8.59d8: 0000000000653000-00000000007fffff 0x0000/0x0004 0x0020000
53e8.59d8: *0000000000800000-00000000008fafff 0x0000/0x0004 0x0020000
53e8.59d8: 00000000008fb000-00000000008fdfff 0x0104/0x0004 0x0020000
53e8.59d8: 00000000008fe000-00000000008fffff 0x0004/0x0004 0x0020000
53e8.59d8: 0000000000900000-000000007ffdffff 0x0001/0x0000 0x0000000
53e8.59d8: *000000007ffe0000-000000007ffe0fff 0x0002/0x0002 0x0020000
53e8.59d8: 000000007ffe1000-00007ff5d1daffff 0x0001/0x0000 0x0000000
53e8.59d8: *00007ff5d1db0000-00007ff5d1dd2fff 0x0002/0x0002 0x0040000
53e8.59d8: 00007ff5d1dd3000-00007ff6fcd8ffff 0x0001/0x0000 0x0000000
53e8.59d8: *00007ff6fcd90000-00007ff6fcd90fff 0x0002/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fcd91000-00007ff6fce01fff 0x0020/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fce02000-00007ff6fce02fff 0x0080/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fce03000-00007ff6fce48fff 0x0002/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fce49000-00007ff6fce49fff 0x0004/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fce4a000-00007ff6fce4afff 0x0008/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fce4b000-00007ff6fce4ffff 0x0004/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fce50000-00007ff6fce50fff 0x0008/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fce51000-00007ff6fce51fff 0x0004/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fce52000-00007ff6fce55fff 0x0008/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fce56000-00007ff6fce9dfff 0x0002/0x0080 0x1000000 \Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe
53e8.59d8: 00007ff6fce9e000-00007ffdf917ffff 0x0001/0x0000 0x0000000
53e8.59d8: *00007ffdf9180000-00007ffdf9180fff 0x0002/0x0080 0x1000000 \Device\HarddiskVolume3\Windows\System32\ntdll.dll
53e8.59d8: 00007ffdf9181000-00007ffdf928ffff 0x0020/0x0080 0x1000000 \Device\HarddiskVolume3\Windows\System32\ntdll.dll
53e8.59d8: 00007ffdf9290000-00007ffdf92d5fff 0x0002/0x0080 0x1000000 \Device\HarddiskVolume3\Windows\System32\ntdll.dll
53e8.59d8: 00007ffdf92d6000-00007ffdf92e0fff 0x0008/0x0080 0x1000000 \Device\HarddiskVolume3\Windows\System32\ntdll.dll
53e8.59d8: 00007ffdf92e1000-00007ffdf92eefff 0x0002/0x0080 0x1000000 \Device\HarddiskVolume3\Windows\System32\ntdll.dll
53e8.59d8: 00007ffdf92ef000-00007ffdf92effff 0x0004/0x0080 0x1000000 \Device\HarddiskVolume3\Windows\System32\ntdll.dll
53e8.59d8: 00007ffdf92f0000-00007ffdf92f2fff 0x0008/0x0080 0x1000000 \Device\HarddiskVolume3\Windows\System32\ntdll.dll
53e8.59d8: 00007ffdf92f3000-00007ffdf9360fff 0x0002/0x0080 0x1000000 \Device\HarddiskVolume3\Windows\System32\ntdll.dll
53e8.59d8: 00007ffdf9361000-00007ffffffeffff 0x0001/0x0000 0x0000000
53e8.59d8: VirtualBox.exe: timestamp 0x5b4cb14e (rc=VINF_SUCCESS)
53e8.59d8: '\Device\HarddiskVolume3\Program Files\Oracle\VirtualBox\VirtualBox.exe' has no imports
53e8.59d8: '\Device\HarddiskVolume3\Windows\System32\ntdll.dll' has no imports
53e8.59d8: supR3HardNtChildPurify: Done after 588 ms and 0 fixes (loop #0).
53e8.59d8: supR3HardNtEnableThreadCreation:
398.3268: Log file opened: 5.2.16r123759 g_hStartupLog=0000000000000004 g_uNtVerCombined=0xa042ee00
398.3268: supR3HardenedVmProcessInit: uNtDllAddr=00007ffdf9180000 g_uNtVerCombined=0xa042ee00
398.3268: ntdll.dll: timestamp 0x7f828745 (rc=VINF_SUCCESS)
398.3268: New simple heap: #1 0000000000b00000 LB 0x400000 (for 1970176 allocation)
398.3268: supR3HardenedWinInitAppBin(0x0): '\Device\HarddiskVolume3\Program Files\Oracle\VirtualBox'
398.3268: System32: \Device\HarddiskVolume3\Windows\System32
398.3268: WinSxS: \Device\HarddiskVolume3\Windows\WinSxS
398.3268: KnownDllPath: C:\windows\System32
398.3268: supR3HardenedVmProcessInit: Opening vboxdrv stub...
398.3268: supR3HardenedWinReadErrorInfoDevice: 'More than one thread in process'
398.3268: Error -5640 in supR3HardenedWinReSpawn! (enmWhat=3)
398.3268: NtCreateFile(\Device\VBoxDrvStub) failed: Unknown Status -5640 (0xffffe9f8) (rcNt=0xe986e9f8)
VBoxDrvStub error: More than one thread in process
53e8.59d8: supR3HardenedWinCheckChild: enmRequest=2 rc=-5640 enmWhat=3 supR3HardenedWinReSpawn: NtCreateFile(\Device\VBoxDrvStub) failed: Unknown Status -5640 (0xffffe9f8) (rcNt=0xe986e9f8)
VBoxDrvStub error: More than one thread in process
53e8.59d8: Error -5640 in supR3HardenedWinReSpawn! (enmWhat=3)
53e8.59d8: NtCreateFile(\Device\VBoxDrvStub) failed: Unknown Status -5640 (0xffffe9f8) (rcNt=0xe986e9f8)
VBoxDrvStub error: More than one thread in process