Hi,
Kindly refer the explain bnelo
1. Yes, this is a global paramter, which means it will affect all the IPSec tunnels.
2. To fragment the df-bit set packets, you can run command ipsec fragmentation ignore df-bit, it allow the device ignor the Don't Fragment (DF) flag bit of original packets.
3. If you are searching a way to unfragment the packets, and no packets dropping, you an run ipsec negotiate-mtu, this comand tune th MTU value of the IPSec negotiation as you set.